Efficacy and Optimal Dose Selection of Intranasal Dexmedetomidine During Breast Lumpectomy Under Local Anaesthesia

• Status: Completed
• Trial end date: 2016-02-01
• Target enrollment: 0
• Participant gender: All

Summary

This trial is going to evaluate the safety and effectiveness of intranasal DEX(dexmedetomidine) in breast lumpectomy under local anaesthesia,and to investigate the optimal dose of intranasal DEX in breast lumpectomy.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tianjin Medical University Cancer Institute and Hospital
• Treatments: Anesthetics; Dexmedetomidine

Criteria

Inclusion Criteria:

• with ASA(American Society of Anesthesiologists) physical status I and II

• scheduled for breast lumpectomy

Exclusion Criteria:

• a history of heart block

• upper respiratory tract infection

• asthma

• allergy to DEX or local anaesthetics

• memory or cognitive dysfunction

• pregnancy

• lack of understanding the consent process

• impaired liver or renal function

• a history of drug or alcohol abuse