Efficacy and Necessity of Time Interval Between Instillation of Two Glaucoma Eye Drops

• Status: Recruiting
• Trial end date: 2022-11-01
• Target enrollment: 0
• Participant gender: All

Summary

According to the American Academy of Ophthalmology's Preferred Practice Pattern on Primary Open Angle Glaucoma, patients should wait five minutes between administering topical drops for intra-ocular pressure reduction.

To date, no study has shown the efficacy of this waiting period. In this study, we aim to establish the clinical significance of keeping a time interval between glaucoma medications.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Sheba Medical Center
• Treatments: Brimonidine Tartrate; Ophthalmic Solutions; Timolol

Criteria

Inclusion Criteria:

Short duration group

• Healthy individuals with negative past ocular history

• able to give consent

Long duration group:

• Diagnosed with primary open angle glaucoma and being treated with two types of IOP reduction drops.

• No other medical ocular history.

• No cognitive disfunction

• able to give consent

• No known arrhythmia

Exclusion Criteria (Both groups):

• Corneal disease preventing from visualization of the angle

• Closed angle

• Pregnant women

• Previous ocular surgery (including cataract or refractive surgery)

• Known allergy to ocular drops used in this study (e.g. brimonidine, timolol)

• History of asthma or arrhythmia