Overview

Efficacy and Mechanisms of Pharmacologic Treatment of Fecal Incontinence

Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to evaluate and compare treatment with fiber and loperamide for fecal incontinence.
Phase:
Phase 2/Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
US Department of Veterans Affairs
VA Office of Research and Development
Treatments:
Antidiarrheals
Calcium polycarbophil
Loperamide
Psyllium
Criteria
Inclusion Criteria:

- weekly fecal incontinence

Exclusion Criteria:

- fecal impaction

- inability to complete a baseline 1-week bowel diary

- rectal prolapse

- any prior radiation to the pelvis

- colo-rectal cancer

- rectal fistula

- inflammatory bowel disease

- neurological diseases (spinal cord injury, multiple sclerosis, Parkinson's disease)

- constipation (<2 bowel movements/week) or total colectomy