Overview

Efficacy and Adverse Effect of Simvastatin Compare to Rosuvastatin in Systemic Lupus Erythematosus (SLE) Patients With Corticosteroid Therapy and High Low-Density Lipoprotein (LDL) Cholesterol Level

Status:
Unknown status

Trial end date:
2010-06-01

Target enrollment:

Participant gender:

Summary

Early statin therapy in SLE patients that have high cholesterol level and other atherosclerosis risk should reduce atherosclerosis and coronary artery events in later course of disease. By the way, statin is used in restricted groups of rheumatologists due to awareness of side effects; myositis and hepatitis, that are frequently found in SLE patients more so than other groups of atherosclerosis patients and reporting data of autoimmune diseases that occur after statin use.

Phase:

Phase 4

Details

Lead Sponsor:

Ramathibodi Hospital

Collaborator:

AstraZeneca

Treatments:

Rosuvastatin Calcium
Simvastatin