Overview

Efficacy Study of FK-506 and Cyclosporine in Vernal Keratoconjunctivits (VKC)

Status:
Completed
Trial end date:
2005-05-01
Target enrollment:
0
Participant gender:
All
Summary
The study was a double-blind, parallel study to compare efficacy of 0.1% tacrolimus ophthalmic ointment vs 2% cyclosporine eye drops in children with vernal keratoconjunctivitis. The duration of the blinded period was 8 weeks followed with 4 weeks of open-period of tacrolimus ointment. The hypothesis was that tacrolimus was as effective as cyclosporine for the treatment of this condition.
Phase:
Phase 2/Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Siriraj Hospital
Treatments:
Cyclosporine
Cyclosporins
Ophthalmic Solutions
Tacrolimus
Tetrahydrozoline
Criteria
Inclusion Criteria:

- patients with clinical diagnosis of vernal keratoconjunctivitis

Exclusion Criteria:

- coexisting ocular diseases such as glaucoma, other corneal disease, ocular infections,
other coexisting systemic diseases