Efficacy Study of Articaine Versus Lidocaine as Supplemental Infiltration in Inflamed Molars
Status:
Completed
Trial end date:
2016-02-01
Target enrollment:
Participant gender:
Summary
The purpose of this trial is to study the ability of a frequently used dental anesthetic
(articaine) to achieve complete numbness of a diseased tooth with the most commonly used
injection technique in the lower jaw (inferior alveolar nerve block: IANB). If this technique
fails, a commonly used supplemental (SUP) technique with one of two possible dental
anesthetics (lidocaine or articaine) will be given to evaluate the success/failure of
complete numbness between the two anesthetics.
Standardized administration of anesthesia is provided by controlled delivery using Midwest
Comfort Control Syringe.
The investigators hypothesize that supplemental infiltration anesthesia with articaine will
give the same success rate as lidocaine in achieving complete pulpal anesthesia in mandibular
molars with irreversible pulpits.
This study consisted of two periods of patient enrollment, treatment and data collection:
Part I: 101 subjects; Part II: 100 subjects.
Phase:
Phase 4
Details
Lead Sponsor:
University of Michigan
Collaborator:
Dentsply International
Treatments:
Anesthetics Anesthetics, Local Carticaine Lidocaine