Efficacy Study of Antiseptic Preoperative Scrubs in Prevention of Postoperative Infections
Status:
Completed
Trial end date:
2008-05-01
Target enrollment:
Participant gender:
Summary
Most cases of infection of clean-contaminated wounds (wounds without gross spillage of
organisms from the gastrointestinal tract) are thought to originate from the skin. Therefore,
it is conceivable that application of an optimal antiseptic agent can reduce the rate of
surgical wound infections. This trial is to compare the impact of disinfecting the skin with
Chloraprep (2%chlorhexidine and 70% isopropyl alcohol) vs. Betadine on the rates of infection
of clean-contaminated surgical wounds. The study will also assess the occurrence of adverse
effects on the skin from either antiseptic agent and the cost-savings associated with the use
of Chloraprep vs Betadine.
Phase:
Phase 3
Details
Lead Sponsor:
Baylor College of Medicine
Collaborators:
Medical College of Wisconsin Michael Debakey Veterans Affairs Medical Center Michael E. DeBakey VA Medical Center US Department of Veterans Affairs VA Office of Research and Development