Efficacy - Safety of Eflornithine-Nifurtimox Combination Versus Eflornithine to Treat Human African Trypanosomiasis
Status:
Completed
Trial end date:
2008-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to compare the therapeutic combination of I.V. eflornithine +
oral nifurtimox to the standard IV eflornithine regimen in terms of therapeutic efficacy and
clinical safety, in patients suffering from Trypanosoma brucei gambiense (Tbg) human African
trypanosomiasis (HAT) in the meningoencephalitic phase.
Phase:
Phase 3
Details
Lead Sponsor:
Drugs for Neglected Diseases
Collaborators:
Epicentre Medecins Sans Frontieres, Netherlands PNLTHA-DRC; PNLTHA-RoC Swiss Tropical & Public Health Institute World Health Organization