Overview

Efficacy, Safety and Evolution of Cardiovascular Parameters in Renal Transplant Recipients

Status:
Completed
Trial end date:
2014-10-30
Target enrollment:
Participant gender:
Summary
The purpose of this study was to determine whether an early Calcineurin Inhibitor (CNI) to everolimus conversion at 10-14 weeks post transplantation improves renal allograft function without compromising efficacy compared to standard CNI treatment in de novo renal allograft recipients. In addition, the study was designed to evaluate the impact of a CNI-free regimen on evolution of cardiovascular parameters in de novo renal allograft recipients
Phase:
Phase 3
Details
Lead Sponsor:
Novartis Pharmaceuticals
Treatments:
Calcineurin Inhibitors
Cyclosporine
Cyclosporins
Everolimus
Sirolimus
Tacrolimus