Efficacy Of Ergocalciferol In Adults According To BMI
Status:
Terminated
Trial end date:
2017-04-01
Target enrollment:
Participant gender:
Summary
Vitamin D insufficiency is an increasing trend in the United States. According to the NHANES
data collection there was a near doubling of patients with vitamin D deficiency in 10 years.
Vitamin D deficiency is associated with several adverse outcomes such as increased fractures,
certain microbial diseases, cardiovascular diseases, and metabolic dysfunction. The
increasing prevalence of vitamin D deficiency has been attributed to the increasing
prevalence of obesity. Several studies have shown that obese patients have lower 25-OH
vitamin D (25-OHD) levels compared to nonobese patients and obese patients require more
vitamin D compared to nonobese patients. The most commonly prescribed medication to replete
vitamin D deficiency is oral ergocalciferol. To date, no prospective trials have been
published to evaluate a standard protocol in the treatment of vitamin D insufficiency in
adults.