Efficacy And Tolerability Of Sub-Anesthetic Ketamine In Postpartum Depression
Status:
Terminated
Trial end date:
2019-09-09
Target enrollment:
Participant gender:
Summary
Postpartum depression is a non-psychotic major or minor depressive episode that occurs during
pregnancy or within 12 months of post-partum period. The nature of symptoms is same as
depressive episode characterized by depressed mood, anxiety, sleep difficulties, suicidal
thoughts, tiredness and diminished interest in pleasurable activities. Severe maternal
depression affects children by increasing the risk of emotional and behavioral and physical
health problems and cognitive difficulties. Thus early screening and intervention is critical
in reducing the negative impact of PND in the mother and child, family and the community.
The purpose of this study is to assess the safety, pharmacokinetics and antidepressant
efficacy of sub-anesthetic dose of intravenous ketamine in perinatal depression.
Phase:
Phase 2
Details
Lead Sponsor:
The University of Texas Health Science Center, Houston