Efficacy Analysis of Anti-VEGF Drugs Combined With Micropulse Laser in the Treatment of Diabetic Macular Edema
Status:
Recruiting
Trial end date:
2024-06-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to clarify the efficacy of anti-vascular endothelial
growth factor (anti-VEGF) drugs combined with subthreshold micropulse laser (SML) therapy on
retinal function and anatomical recovery in patients with diabetic macular edema (DME). The
main questions it aims to answer are:
- To clarify the efficacy of anti-VEGF drugs combined with SML therapy on retinal function
and anatomical recovery in DME patients.
- To explore the changes in visual acuity and optical coherence tomography angiography
(OCTA) parameters before and after the treatment of DME with anti-VEGF drugs combined
with SML, and further explore the changes in morphological characteristics of retinal
microvessels and the potential treatment mechanism.
Participants will randomly be given Intravitreous injection of anti-VEGF drugs or anti-VEGF
drugs combined with SML therapy. All participants will be followed up for 6 months after
treatment.
Phase:
N/A
Details
Lead Sponsor:
Second Affiliated Hospital, School of Medicine, Zhejiang University