Effects on the Immune System of Anti-HIV Drugs in Patients Recently Infected With HIV
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The purpose of this study is to find out whether these powerful combinations of anti-HIV
drugs are safe and effective for use in patients in the early stages of HIV infection and to
find out how patients' immune systems react to HIV and anti-HIV drugs.
Doctors generally treat patients in the early stages of HIV infection with the same anti-HIV
drugs taken by patients who have had HIV for a long time. These drugs lower the level of HIV
in the blood. However, doctors do not know whether patients who take anti-HIV drugs in the
early stages of HIV infection actually live longer or have fewer AIDS-related diseases. This
study will help doctors answer these questions. In the main study, doctors will look at how 2
different anti-HIV drug combinations affect the immune system. In the 2 substudies, doctors
will look at how the body reacts to the hepatitis B vaccine and the tetanus vaccine. These
substudies may help doctors learn how HIV-infected patients respond to new infections.
Phase:
N/A
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)