Overview

Effects of a Kappa Agonist on Hot Flashes in Menopausal Women

Status:
Completed
Trial end date:
2013-07-01
Target enrollment:
Participant gender:
Summary
Studies suggest that kappa agonists (KA) and peripherally restricted kappa agonists (PRKAs) may affect thermoregulation. This pilot study has the aim to establish proof of concept regarding efficacy of an oral kappa agonist (KA) for the treatment of menopausal hot flashes.
Phase:
Phase 1
Details
Lead Sponsor:
University of Washington
Collaborators:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Center for Advancing Translational Science (NCATS)
National Center for Complementary and Integrative Health (NCCIH)
National Institute on Aging (NIA)
Office of Research and Women's Health (ORWH)
Office of Research on Women's Health (ORWH)
Treatments:
Naloxone
Pentazocine