Background:
- Atopic dermatitis, or eczema, is a chronic skin disorder. Patients sometimes have
infections with S. aureus bacteria. Researchers want to study how eczema treatments affect
the number and the type of bacteria on the skin.
Objectives:
- To study the effect of eczema treatments on skin bacteria.
Eligibility:
- Individuals between 2 and 25 years of age who have moderate to severe atopic dermatitis.
- Healthy volunteers between 18 and 40 years of age with no history of eczema.
Design:
- Participants will be screened with a physical exam and medical history. Research samples
will be collected. Skin biopsies may also be performed.
- All participants will be assigned to one of several study groups.
- This study will last for up to 1 year. Healthy volunteers must not have taken
antibiotics in the year before the start of the study.
- All participants will have regular study visits during their 1-year participation. More
research samples will be collected at these visits.
Phase:
Phase 2
Details
Lead Sponsor:
National Cancer Institute (NCI) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)