Effects of Tiotropium on Walking Capacity in Patients With COPD
Status:
Completed
Trial end date:
2010-08-01
Target enrollment:
Participant gender:
Summary
This study was designed to test the following hypothesis:
A) The acute and long-term (3 weeks) bronchodilator-induced changes in exercise tolerance and
in the physiological response during the endurance shuttle walk will be greater with
tiotropium compared to placebo in COPD patients.
B) Three weeks of bronchodilation will be associated with increase activity of daily living
as evaluated using the London Chest Activity Daily Living scale.