Overview

Effects of Thiazide Diuretics on Sympathetic Nervous System in Hypertension

Status:
Completed
Trial end date:
2013-01-01
Target enrollment:
Participant gender:
Summary
Thiazide medications are often prescribed for individuals with high blood pressure, but research has shown that they may increase an individual's risk of developing diabetes. While it is unknown exactly how thiazide causes this response, it is likely that the nervous system is somehow involved. This study will evaluate the role of the nervous system in sugar metabolism, as well as determine the effect of thiazide and other medications on individuals with high blood pressure.
Phase:
Phase 4
Details
Lead Sponsor:
University of Texas Southwestern Medical Center
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)
Treatments:
Chlorthalidone
Eplerenone
Irbesartan
Quinapril
Spironolactone