Effects of Terlipressin When Usual Somatostatin or Octreotide Dose Fails

• Status: Unknown status
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: All

Summary

To observe and access the Effects and safety of terlipressin or high dose somatostatin/octreotide when usual dose somatostatin/octreotide fail to achieve hemostasis in patients with acute variceal bleeding.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shanghai Zhongshan Hospital
• Treatments: Lypressin; Octreotide; Somatostatin; Terlipressin

Criteria

Inclusion Criteria:

• Cirrhosis patients admitted to Emergency Department because of acute variceal bleeding

Exclusion Criteria:

• No signs of variceal bleeding are found by endoscopy or portal hypertensive gastropathy is responsible for the bleeding

• Patients undergo endoscopy after 72h from the beginning of acute variceal bleeding

• Patients with hepatorenal syndrome

• Patients with ischemia organic cardiopathy (including myocardial infarction or unstable angina pectoris) or myocardial ischemia indicated by ECG in the past 6 months

• Patients allergic to/with contraindications of vasoactive drugs