Effects of Telomerase Reactivation With Danazol in Ovarian Function.
Status:
Recruiting
Trial end date:
2022-06-01
Target enrollment:
Participant gender:
Summary
This project explores the implication of the telomere pathway in ovarian premature and
regular aging. Telomere length and maintenance underlie several biological processes such
cancer, aging, human diseases and the biology of stem cells. The reactivation of telomerase
should lead to a rejuvenation of the ovarian tissue and the improvement of fertility.
The correlation of telomeric factors in blood and granulosa cells will be studied with the
aim of finding telomeric biomarkers of ovarian aging.