Effects of Switching From Racemic Methadone to R-methadone on QTc Intervals

• Status: Active, not recruiting
• Trial end date: 2022-04-30
• Target enrollment: 0
• Participant gender: All

Summary

Effects of switching from racemic methadone to R-methadone on serum methadone concentrations and QTc intervals

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Oslo University Hospital
• Treatments: Methadone

Criteria

Inclusion Criteria:

• Stabilized on daily methadone dose

• Not using other drugs of abuse

• QTc-time recorded automatically, patient inclusion if QTc interval was greater or equal to 450 ms

• Older than 18 years

• Can sign and understand a written Consent

Exclusion Criteria:

• Can not cooperate regarding observed daily drug intake

• Serious psychiatric disease

• Untreated serious somatic disease

• Pregnancy