Overview Effects of Statins on Pro- and Antioxidant Status : Link With Statin-Associated Myopathy. Status: Completed Trial end date: 2007-04-01 Target enrollment: Participant gender: Summary To evaluate the effects of a 8-week treatment with 80 mg/day simvastatin on prooxidant and antioxidant status at rest and after exercise, on mitochondrial respiration and calcium release in skeletal muscle, and on aƩrobic aptitude in 24 healthy male subjects. Phase: N/A Details Lead Sponsor: University Hospital, MontpellierTreatments: AntioxidantsSimvastatin