Overview

Effects of Smoked Marijuana on Risk Taking and Decision Making Tasks

Status:
Completed
Trial end date:
2008-03-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to investigate the effects of smoked marijuana on both risk taking and decision making tasks.
Phase:
Phase 1
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
New York State Psychiatric Institute
Collaborator:
National Institute on Drug Abuse (NIDA)
Treatments:
Dronabinol
Criteria
Inclusion Criteria:

- Current marijuana use

- 21-45 years of age

- Practicing an effective form of birth control

- Not seeking treatment for marijuana use

Exclusion Criteria:

- Current, repeated illicit drug use other than marijuana

- Presence of significant medical illness (e.g., diabetes, cardiovascular disease,
hypertension)

- Laboratory tests outside normal limits that are clinically unacceptable to the study
physician (BP > 140/90; hematocrit < 34 for women, < 36 for men)

- Significant adverse reaction to marijuana

- Current parole or probation

- Pregnancy or current lactation

- Recent history of significant violent behavior

- Major current Axis I psychopathology (e.g., mood disorder with functional impairment
or suicide risk, anxiety disorder, schizophrenia

- History of heart disease

- Current use of any over-the-counter or prescription medication from which the
volunteer cannot be withdrawn