Effects of Sitaglpitin on Endothelial Function During the OGTT in T2DM
Status:
Unknown status
Trial end date:
2017-07-01
Target enrollment:
Participant gender:
Summary
To investigate whether single administration of sitaglitpin can restore acute endothelial
dysfunction and ameliorate impaired increase of the number of endothelial progenitor cells
(EPCs) after oral glucose loading in patients with T2DM.
To compare the effect of sitagliptin and glimepiride on endothelial function evaluated by
flow-mediated vasodilatation (FMD) and the number of circulating EPCs in patients with T2DM.