Effects of Sitagliptin on Gastric Emptying in Healthy Subjects
Status:
Completed
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the effects of the drug, sitagliptin, on the rate
at which the stomach empties, and the release of gut hormones and blood glucose
concentrations, after a mashed potato meal in healthy subjects. Sitagliptin has been shown to
reduce the blood glucose (sugar) response to a meal and this may potentially be due to
slowing of stomach emptying. This is particularly relevant to people who have diabetes, in
whom normalization of elevated blood glucose levels is important to maintain health.