Effects of Single Doses of Liraglutide and Dapagliflozin on Hyperglycemia and Ketogenesis in Type 1 Diabetes
Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
1. To compare levels of ketone bodies (beta-hydroxybutyrate and acetoacetate) in plasma and
urine following a single dose treatment of either liraglutide 1.8mg,dapagliflozin 10mg
or placebo in insulinopenic state.
2. To compare plasma levels of free fatty acid, glucagon, hs-CRP, Il-6 and IL-1 before and
after administration of liraglutide/Dapagliflozin/placebo.