Effects of Short-term Growth Hormone in HIV-infected Patients
Status:
Completed
Trial end date:
2012-11-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to examine the short-term effects of two different doses of
growth hormone, compared to treatment with growth hormone releasing hormone, on the brain's
secretion of growth hormone and the body's glucose metabolism. We hypothesize that growth
hormone administration will alter the body's endogenous pulsatile growth hormone secretion
and that higher dose growth hormone may decrease insulin sensitivity. We hypothesize that
growth hormone releasing hormone will augment endogenous GH pulsatility and be neutral to
insulin sensitivity.
Phase:
N/A
Details
Lead Sponsor:
Massachusetts General Hospital
Collaborator:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)