Effects of Short-term Atorvastatin Treatment on Vaccination Efficacy in Nonresponder Persons to Hepatitis B Vaccine

• Status: Unknown status
• Trial end date: 2012-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether short-term Atorvastatin can increase the immunity response to hepatitis B vaccination in vaccine Nonresponders.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Nematollah Jonaidi Jafari
• Treatments: Atorvastatin; Atorvastatin Calcium; Vaccines

Criteria

Inclusion Criteria:

• Previous 3 dose hepatitis B vaccination

• Negative HBc Ab

• Negative HBs Ag

• HBs Ab less than 10 in ELIZA

Exclusion Criteria:

• positive serologic evidence of Hepatitis B infection

• Chronic use of Atorvastatin

• Immunosuppressive Disease