Effects of Sevoflurane in Subanesthetic Concentrations on the Forearm Perfusion

• Status: Unknown status
• Trial end date: 2008-12-01
• Target enrollment: 0
• Participant gender: Male

Summary

Sevoflurane preconditioning and cardiovascular protection against ischemia/reperfusion injury.

Study hypothesis: The volatile anesthetic sevoflurane at subanesthetic concentrations achieves endothelial protection against ischemia/reperfusion injury and reduces inflammatory markers in the circulation

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Zurich
• Treatments: Sevoflurane

Criteria

Inclusion criteria: male

• Non-smoker

• No asthma

• NPO

• Volunteer

Exclusion criteria:

• Female

• Chronic medication

• Asthma

• Smoking