Effects of Sevoflurane and Propofol on Optic Nerve Sheath Diameter During Laparoscopic Gynecologic Surgery

• Status: Enrolling by invitation
• Trial end date: 2020-06-01
• Target enrollment: 0
• Participant gender: Female

Summary

Intracranial pressure（ICP) increases during laparoscopic gynecologic surgery increase (ICP) and may alter optic nerve sheath diameter(ONSD).This study measures ONSD in different team because sevoflurane and propofol have different effects on ICP.Half of participants will receive sevoflurane anesthesia,while the other half undergo propofol anesthesia.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Obstetrics & Gynecology Hospital of Fudan University
• Treatments: Propofol; Sevoflurane

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists physical status diagnosed as I or II

Exclusion Criteria:

• neuromuscular diseases;laboratory abnormalities in electrolytes; liver and kidney dysfunction;allergy to general anesthetics;pregnancy;ocular lesions including ocular trauma, optic neuritis, optic nerve tumor.