Effects of Rosiglitazone on Bone in Postmenopausal Diabetic Women

• Status: Completed
• Trial end date: 2006-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to evaluate the effect of rosiglitazone on bone metabolism and to assess the association between the changes in bone turnover parameters and plasma cytokine levels in postmenopausal diabetic women

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Baskent University
• Treatments: Rosiglitazone

Criteria

Inclusion Criteria:

• Newly diagnosed type 2 diabetes mellitus

• Postmenopausal period

Exclusion Criteria:

• Recent fracture or osteoporosis

• Drugs that may affect calcium or bone metabolism or drugs known to interfere with cytokine release

• Thyroid, parathyroid, pituitary, nutritional, inflammatory, hepatic, renal, or neoplastic disorders

• Severe cardiovascular disease