Effects of Repeated Doses of Foliglurax on Drug Metabolizing Enzymes in Healthy Subjects

• Status: Completed
• Trial end date: 2020-04-03
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to help determine which types of drugs that may interact with foliglurax

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: H. Lundbeck A/S
• Treatments: Midazolam; Montelukast

Criteria

Inclusion Criteria:

• Healthy men and women with a body mass index (BMI) of ≥ 18.5 and ≤ 30 kg/m2 and a minimum body weight of 60 kg for men and 50 kg for women.

• Women of child-bearing potential will have a confirmed non-pregnant and non-lactating status.

Exclusion Criteria:

• The subject has a regular intake of more than 500 mg of caffeine per day or impossibility to stop intake, on holidays for example, without headaches forcing to take caffeine again.

Other in- and exclusion criteria may apply