Effects of Remimazolam on the Intraoperative Hemodynamics in Bypass Surgery

• Status: Not yet recruiting
• Trial end date: 2023-12-30
• Target enrollment: 0
• Participant gender: All

Summary

This study is a randomized, controlled trial. A total of 72 patients will be randomized to receive remimazolam anesthesia or balanced anesthesia (propofol + desflurane) during extracranial-intracranial bypass surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital
• Treatments: Anesthetics

Criteria

Inclusion Criteria:

• Patients who undergo elective extracranial-intracranial bypass surgery

• American Society of Anesthesiologists grade 1,2,3

• Age > 18 years old

Exclusion Criteria:

• Refuse to participate to the study

• American Society of Anesthesiologists grade 4

• Body Mass Index < 18.5 kg/m2 or > 35 kg/m2

• Allergic history of benzodiazepine

• Pregnant

• Acute narrow-angle glaucoma

• Shock or Coma

• Acute alcohol addicted

• Obstructive sleep apnea

• dependency on alcohol or drug

• Severe acute respiratory insufficiency

• Hypersensitivity to Dextran 40