Effects of Progesterone on IV Nicotine-Induced Changes in Hormones and Subjective Ratings of Stimulant Drug Effect
Status:
Suspended
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The proposed clinical studies will analyze the interactions between progesterone, nicotine,
alterations in endocrine hormones, mood and cardiovascular measures. It is hypothesized that
the administration of progesterone at a dose that mimics luteal phase levels in normal
cycling women will diminish the positive subjective effects of nicotine, as has been
consistently observed for cocaine. This novel approach could have direct implications for
facilitating smoking cessation treatment in women of reproductive age
Phase:
N/A
Details
Lead Sponsor:
Mclean Hospital
Treatments:
Central Nervous System Stimulants Hormones Nicotine Progesterone