Effects of Preemptive Paracetamol and Ibuprofen on Headache and Myalgia in Patients After Electroconvulsive Therapy

• Status: Completed
• Trial end date: 2019-02-10
• Target enrollment: 0
• Participant gender: All

Summary

The primary aim this prospective, randomized, double-blind, placebo-controlled clinical trial is to compare the analgesic effects of preemptive intravenous paracetamol and ibuprofen on headache and myalgia, and secondary aim is to evaluate the effects on hemodynamics, duration of seizure and postoperative side effects in patients who underwent electroconvulsive therapy .

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Inonu University
• Treatments: Acetaminophen; Ibuprofen

Criteria

Inclusion Criteria:

• Patients with major depression

• Patients with American Society of Anesthesiologists (ASA) scores I or II

• Between 18-65

Exclusion Criteria:

• Patients with ASA scores III/IV,

• Under the age of 18,

• Over the age of 65,

• Myocardial infarction,

• Congestive heart failure,

• Pulmonary disease,

• Stroke history,

• Bleeding disorder,

• Hepatic and renal dysfunction,

• Pregnant,

• Migraine history,

• Allergy of nonsteroidal anti-inflammatory drugs, paracetamol, propofol,

• Neuromuscular disease,

• Peptic ulcer disease,

• Intracranial hypertension,

• Glaucoma

• Patients who did not give informed consent