Overview

Effects of Photobiomodulation and Topical Diclofenac on Inflammation and Pain in Knee Osteoarthritis (EPIC-KO)

Status:
NOT_YET_RECRUITING

Trial end date:
2026-07-01

Target enrollment:

Participant gender:

Summary

This study aims to compare the effects of combined treatments-dual-wavelength photobiomodulation (PBM) with or without topical diclofenac-on inflammation, pain, and joint function in patients with knee osteoarthritis (OA). It also seeks to determine the synergistic effect of PBM plus topical diclofenac on inflammatory markers, pain scores, and functional outcomes.

Phase:

PHASE2

Details

Lead Sponsor:

University of Florida

Treatments:

Diclofenac
Low-Level Light Therapy
Phototherapy