Effects of Oxytocin on the Functional Architecture of the Brain Before and After Prolonged Naturalistic Fear Induction

• Status: Recruiting
• Trial end date: 2025-12-01
• Target enrollment: 0
• Participant gender: Male

Summary

The main aim of the pharmacological resting-state fMRI study is to investigate the modulatory effects of intranasal Oxytocin (24IU) on task and intrinsic functional connectivity before and after prolonged exposure to naturalistic fear induction via a movie.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Electronic Science and Technology of China
• Treatments: Oxytocin

Criteria

Inclusion Criteria:

• Healthy subjects without past or current psychiatric or neurological disorders

• Right-handedness

• Normal or corrected-normal version

Exclusion Criteria:

• History of head injury

• Medical or psychiatric illness

• Hypertension

• General cardio-vascular alteration or diseases

• Allergy against medications

• Visual or motor impairments

• Claustrophobia

• Drug addiction

• Nicotine dependence

• FMRI contradictions