Context: The treatment of alcoholism is a challenge for psychiatrists and patients. Some
studies have shown that alcohol alters the environment of the membranes, mainly by modifying
their permeability through the lipid fraction. These lipids are known as essential fatty
acids (EFA) because they are obtained only through the diet, as the human body is unable to
synthesize them. Linolenic acid (LA), or omega 6, and alpha-linolenic acid (ALA), or omega 3,
are polyunsaturated fatty acids (PUFAs). Finally, ethanol changes the absorption and
metabolism of PUFAs, and it's supplementation may be helpful for alcohol dependence recovery.
Objective: to assess the effectiveness of PUFAs supplementation in the treatment of alcohol
dependent patients.
Phase:
Phase 3
Details
Lead Sponsor:
Federal University of São Paulo
Collaborators:
Associacao Fundo de Incentivo a Psicofarmcologia Fundação de Amparo à Pesquisa do Estado de São Paulo