Effects of Noninvasive Ventilation Compared to Salbutamol
Status:
Completed
Trial end date:
2018-12-20
Target enrollment:
Participant gender:
Summary
Asthma is a chronic inflammatory disease characterized by recurrent and reversible episodes
of airway obstruction. Drug treatment usually includes inhaled corticosteroids and bronchial
dilators, which often do not have adequate adherence. These acute episodes of
bronchoconstriction can most often occur with hyperinflation and for decades the mechanisms
that lead to hyperinflation have been studied, as well as increasingly modern ways of
evaluating and treating these mechanisms. Noninvasive ventilation is increasingly occupying
its space as a non-pharmacological resource in the treatment of asthma, initially as an
adjunct in an attempt to help medication have its effect reached in the crisis, but this
feature has been showing signs of having an even greater action which can even collaborate in
reversing the crisis by not only giving time for pharmacological action. Recognizing these
potential effects of this widely used resource and understanding its action on lung function
and the reversal of exacerbation is part of this scientific process.