Overview

Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients

Status:
Completed
Trial end date:
2015-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine if Nebivolol improves microvascular perfusion in skeletal muscle during exercise in hypertensive patients and whether this improvement is accompanied by reduction in vascular oxidative stress or increased endothelial nitric oxide synthase (eNOS) expression in humans.
Phase:
Phase 4
Details
Lead Sponsor:
University of Texas Southwestern Medical Center
Collaborator:
Forest Laboratories
Treatments:
Hydrochlorothiazide
Metoprolol
Nebivolol
Nitric Oxide
Polystyrene sulfonic acid