Effects of Nebivolol on Exercise Tolerance and Left Ventricular Systolic and Diastolic Function
Status:
Completed
Trial end date:
2014-05-01
Target enrollment:
Participant gender:
Summary
The goal of this pilot study is to effectively treat hypertension in subjects with either
known or newly diagnosed hypertension and concurrent evidence of diastolic dysfunction. Due
to the unique properties of nebivolol, it is hypothesized that there will be improvements in
left ventricular (LV) systolic and diastolic function manifesting as increase exercise
capacity in this patient population with primarily LV diastolic dysfunction. The present
study was performed to determine the effects of nebivolol on blood pressure, exercise
tolerance and parameters of left ventricular systolic and diastolic function in a group of
hypertensive patients with echocardiographic evidence diastolic dysfunction.