Effects of Metformin Treatment on Myocardial Efficiency in Patients With Heart Failure
Status:
Completed
Trial end date:
2018-02-14
Target enrollment:
Participant gender:
Summary
The study evaluates the effects of metformin treatment on myocardial efficiency in heart
failure patients. 36 patients will be randomized to three months of metformin or placebo
treatment in addition to their regular therapy.
Hypothesis: Treatment with metformin in patients with heart failure has direct or indirect
beneficial effects on left ventricular myocardial oxidative metabolism, myocardial efficiency
and contractile function.