Effects of Mesna on Homocysteine in Kidney Failure
Status:
Completed
Trial end date:
2007-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to examine the effect of a drug called mesna on the
removal of homocysteine from blood during dialysis. Homocysteine is an amino acid (protein
building block) found in the blood of all people, however it is considerably elevated in
dialysis patients. People with increased levels of homocysteine in their blood are at
increased risk of developing plaque buildup in their arteries and other related problems such
as heart attack and stroke. This study will determine if mesna can improve the rate of
homocysteine removal from blood during dialysis.