Effects of Mepivacaine on the Neurological Sequelae of Cerebral Infarction
Status:
Not yet recruiting
Trial end date:
2024-03-15
Target enrollment:
Participant gender:
Summary
A patient, suffering from cortical blindness after a bi-occipital infarction 1 year earlier,
regained near-normal vision in the right visual hemifield a few minutes after subcutaneous
administration of mepivacaine. The effect was maintained for several days, and was repeated
with each injection of mepivacaine. This clinical improvement is associated with functional
changes in the peri-lesional areas on resting-state functional MRI.
The investigator team hypothesizes that in some patients with chronic neurological symptoms
of stroke, we will observe a favorable response to subcutaneous mepivacaine injection.