Effects of Lutein and Zeaxanthin Supplementation on Age-related Macular Degeneration
Status:
Unknown status
Trial end date:
2012-10-01
Target enrollment:
Participant gender:
Summary
Lutein is one of oxygenated carotenoids. Over the past few years, there has been increased
interest in evaluating the effect of lutein for optimizing eye health. A large number of
epidemiological studies support the notion that the high intake dietary of lutein is strongly
associated with a decreased relative risk of AMD.Moreover, findings from initial
observational studies have now been followed by placebo-controlled intervention trials
showing that dietary modification and supplementation with lutein result in increasing the
macular pigment optical density, and may help to improve visual function in patients
suffering from AMD.Currently, nutritional status and background information of lutein and
zeaxanthin in Chinese population is lack. Little is known about the preventive and therapy
benefits of lutein on visual function in the AMD populations. In particular, the effect on
visual function of relatively certain doses of lutein and zeaxanthin is unknown. Therefore,
the objective of the present study was to examine the effect of consuming different doses of
lutein on MPOD and visual function in AMD.