Effects of Lutein Supplementation on Oxidative Stress and Inflammation in Healthy Nonsmokers
Status:
Unknown status
Trial end date:
2012-08-01
Target enrollment:
Participant gender:
Summary
Lutein is one of oxygenated carotenoids. Over the past few years, there has been increased
interest in evaluating the effect of lutein for optimizing immune functions. A large number
of epidemiological studies support the notion that a high intake of lutein is associated with
a reduced risk of coronary heart disease and certain types of cancer. The biological
mechanisms for the protective effects of this carotenoid, including powerful modulation of
functions and antioxidant properties, are only partially known. Although several nutrients
and phytochemicals have been shown to modulate immune functions in humans, few studies have
investigated the role of lutein consumption. No information is available as to whether lutein
supplementation could be protective against oxidative stress. Therefore, the objective of the
present study was to examine the effect of consuming different doses of lutein on oxidative
stress in healthy subjects.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Peking University
Collaborators:
Health Science Center of Xi'an Jiaotong University Health Science Center of Xi’an Jiaotong University