Effects of Low Dose Aspirin in Bipolar Disorder (The A-Bipolar RCT)
Status:
Not yet recruiting
Trial end date:
2023-01-01
Target enrollment:
Participant gender:
Summary
Despite currently available treatment, a large proportion of patients with bipolar disorder
(BD) suffer from affective symptoms, impaired psychosocial and cognitive function.
Inflammation seems to be involved in the pathogenesis of BD and preliminary data suggest that
low-dose Aspirin may have beneficial effects. The objective of this RCT is to investigate
whether add on of low dose aspirin versus placebo add on to standard drug treatment improves
mood stabilisation and other critical patient outcomes in patients with BD and whether its
principal effects are antimanic, antidepressant or prophylactic against relapse.
randomized double-blinded placebo-controlled trial will investigate whether augmentation with
low dose Aspirin to standard drug treatment improve mood stabilization.