Overview

Effects of L-arginine on Myocardial Energetic Efficiency and Global Longitudinal Strain

Status:
Recruiting
Trial end date:
2021-08-30
Target enrollment:
Participant gender:
Summary
The study is designed to evaluate the effects of L-arginine on myocardial structure and function and circulating microRNAs in patients with arterial hypertension. The study will analyze the impact of 4 weeks treatment randomized to L-arginine or placebo, on mechanical-energy efficiency (MEE) and longitudinal strain in patients with arterial hypertension. The investigators will also assess whether the changes in MEE and strain induced by L-arginine treatment is associated with changes in circulating micro RNAs.
Phase:
Phase 4
Details
Lead Sponsor:
Federico II University
Collaborators:
Prof. Costantino Mancusi
Prof. Raffaele Izzo