Effects of Ketamine On Precipitated Opioid Withdrawal Under General Anaesthesia

• Status: Completed
• Trial end date: 2006-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether low-dose ketamine infusion is effective in suppressing the symptoms of opiate withdrawal during rapid opiate antagonist induction (RAI).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Vilnius University
• Treatments: Ketamine

Criteria

Inclusion Criteria:

• Diagnosed opiate dependence according to ICD 10 and/or DSM 4;

• Duration of substance abuse more than 1 year

• No or minor co-morbidities;

• Grade I-II according to physical status classification system of American Society of Anesthesiologists.

Exclusion Criteria:

• Current history of long acting opiate or poly-substance abuse;

• Acute medical or surgical condition;

• Pregnancy;

• Breastfeeding.