Effects of Intraoperative, Goal-directed Crystalloid vs. Colloid Fluid Resuscitation on Free Flaps
Status:
Completed
Trial end date:
2018-09-19
Target enrollment:
Participant gender:
Summary
Maintaining satisfactory tissue perfusion is an essential of success during reconstructive
free flap surgery following malign oral cavity tumours. Intra- and postoperative
goal-directed fluid therapy is an appropriate tool for that. Continuous cardiac output
monitoring based fluid loading (complemented with vasopressor and/or inotropes if necessary)
might be superior to conventional, central venous and arterial pressure monitoring in terms
of morbidity, complications, optimal fluid balance and days spent in hospital. However, there
is no data describing the effects of goal-directed fluid therapy (crystalloid or colloid) on
microcirculation of free flaps implanted in the oral cavity during the post-operative period.
The aim of this study is to observe the effects of continuous macrohaemodynamic monitoring
based, goal-directed fluid therapy on microcirculation of forearm flaps during the
perioperative period.
Phase:
N/A
Details
Lead Sponsor:
Szeged University
Collaborators:
Department of Oral and Maxillofacial Surgery, University of Szeged Institute of Surgical Research, University of Szeged