Overview

Effects of Intensive cART During Acute/Early HIV Infection

Status:
Completed
Trial end date:
2014-09-01
Target enrollment:
Participant gender:
Summary
This trial will investigate the efficacy and safety of intensified antiretroviral treatment that includes raltegravir and maraviroc during the early stages of HIV infection. With the proven efficacy of these antiviral drugs in pre- and post-clinical trials, we would like to investigate the ability of the combination of raltegravir and maraviroc plus a standard HAART backbone to further decrease the viral load in acutely infected treated HIV infected individuals.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
University of Toronto
Collaborators:
Maple Leaf Medical Clinic
St. Michael's Hospital, Toronto
Unity Health Toronto
Treatments:
Emtricitabine
Lopinavir
Maraviroc
Raltegravir Potassium
Ritonavir
Tenofovir